Searchable abstracts of presentations at key conferences in endocrinology

ea0041gp57 | Cardiovascular endocrinology | ECE2016

Prioritizing drug targets for non-alcoholic fatty liver disease based on comorbidity network analysis

Nguyen Thanh-Phuong , Sauter Thomas , Caberlotto Laura , Lammert Frank , Schneider Jochen G

Background and aims: Non alcoholic fatty liver disease (NAFLD) is highly associated with other components of the metabolic syndrome, in particular obesity and diabetes. However, systematic network medicine approach of the complex phenotypic dependencies and comorbidities has yet to be performed. Our aim now is to identify novel drug targets for NAFLD treatment by a systematic in silico network analysis.Methods: We constructed an interaction network of cu...